Document Detail


Observations on the presentation, diagnosis, and treatment of interstitial cystitis in men.
MedLine Citation:
PMID:  11378046     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article presents and evaluates the symptoms, presentation, diagnosis, and treatment of men with interstitial cystitis (IC). A retrospective chart review and an interview of all men in our practice diagnosed with IC since 1990 was performed. The patients' presenting symptoms, physical findings, clinical evaluation, and responses to therapy were reviewed. A total of 52 men were identified during the study who met the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) criteria for diagnosis of IC. The most common referral diagnosis was prostatitis with the most common predominant symptoms being suprapubic pain with urinary frequency and dysuria. A significant number of male patients also developed sexual dysfunction. All patients met the NIDDK criteria for a diagnosis of IC. Multiple therapies were used for the treatment of these patients over the study period. Five patients were initially treated with dimethyl sulfoxide (DMSO) as a sole agent; however, all intravesically treated patients eventually failed this form of therapy. A total of 37 of 52 patients were treated with multidrug oral therapy. Findings showed that 80% of patients achieved >75% improvement in their symptomology at 6 months of follow-up with a durable response at 1 year. IC in men is probably underdiagnosed and is most commonly misdiagnosed as prostatitis. The patient's presentation is analogous to that in the female population allowing for gender differences. The patients responded well to multidrug oral therapy.
Authors:
J B Forrest; Q Vo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Urology     Volume:  57     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2002-02-18     Completed Date:  2002-03-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  26-9     Citation Subset:  IM    
Affiliation:
Urologic Specialists of Oklahoma, Inc, Tulsa, Oklahoma, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Analgesics, Non-Narcotic / therapeutic use
Cystitis, Interstitial* / complications,  diagnosis,  drug therapy
Dimethyl Sulfoxide / therapeutic use
Humans
Male
Middle Aged
Pelvic Pain / drug therapy,  etiology
Retrospective Studies
Chemical
Reg. No./Substance:
0/Analgesics, Non-Narcotic; 67-68-5/Dimethyl Sulfoxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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