Document Detail


Observations on mechanisms of ventricular tachycardia in man.
MedLine Citation:
PMID:  181169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifty patients with sustained ventricular tachycardia were studied by endocavitary recordings and programmed electrical stimulation. Of 29 patients in whom tachycardia could be initiated, 18 had chronic coronary artery disease and eight had no detectable heart disease. Of 35 patients in whom the tachycardia could be terminated by premature ventricular stimuli, 21 had chronic coronary artery disease and eight had no detectable heart disease. Initiation of tachycardia was facilitated in 18 of 21 patients by pacing the ventricle at the slowest possible pacing rate. An inverse relation was found between the prematurity of the tachycardia-initiating premature beat and the interval between the premature beat and the first beat of tachycardia, a finding suggestive of a re-entry mechanism. The role of the specific conduction system in initiation and during tachycardia remains unknown. Stimulation site was found to affect initiation and termination of tachycardia and width of tachycardia zone.
Authors:
H J Wellens; D R Düren; K I Lie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  54     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1976 Aug 
Date Detail:
Created Date:  1976-09-25     Completed Date:  1976-09-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  237-44     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Action Potentials
Adolescent
Adult
Aged
Atrioventricular Node / physiopathology
Bundle of His / physiopathology
Electric Stimulation
Electrocardiography
Evoked Potentials
Female
Heart Block / physiopathology
Heart Ventricles / physiopathology*
Humans
Male
Middle Aged
Myocardial Contraction
Myocardial Infarction / physiopathology
Refractory Period, Electrophysiological
Synaptic Transmission
Tachycardia / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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