Document Detail


Observations in man of hypoglycaemia during selective and non-selective beta-blockade.
MedLine Citation:
PMID:  13497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The acute hypoglycaemic reaction is accompanied by a rise in systolic and a slight fall in diastolic blood pressure and a tachycardia. In contrast, during beta-blockade with propranolol there is a rise of both systolic and diastolic blood pressures and bradycardia. Restoration of blood glucose to normal is delayed. With metoprolol there is a lesser increase in diastolic blood pressure and a slight tachycardia. Restoration of the blood glucose to normal is little delayed. When patients liable to hypoglycaemia require a beta-blocking agent, it is suggested that a selective blocker such as metoprolol should be used.
Authors:
N M Davidson; R J Corrall; T R Shaw; E B French
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scottish medical journal     Volume:  22     ISSN:  0036-9330     ISO Abbreviation:  Scott Med J     Publication Date:  1977 Jan 
Date Detail:
Created Date:  1977-04-01     Completed Date:  1977-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2983335R     Medline TA:  Scott Med J     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  69-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adrenergic beta-Antagonists / adverse effects*
Adult
Blood Glucose / metabolism
Blood Pressure / drug effects
Humans
Hypoglycemia / chemically induced*
Male
Metoprolol / administration & dosage,  metabolism
Middle Aged
Propranolol / administration & dosage,  metabolism
Tachycardia / chemically induced
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Blood Glucose; 37350-58-6/Metoprolol; 525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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