Document Detail

[Observations on human parvovirus B19 infection diagnosed in 2011].
MedLine Citation:
PMID:  23204301     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The incidence of human parvovirus B19 infection is unknown.
AIM: A retrospective analysis of clinical and laboratory findings was carried out in patients diagnosed with human parvovirus B19 infection in 2011 in a virologic laboratory of a single centre in Hungary.
METHODS: Clinical and laboratory data of patients with proven human parvovirus B19 infection were analysed using in- and out-patient files.
RESULTS: In 2011, 72 patients proved to have human parvovirus B19 infection with the use of enzyme immunoassay. The clinical diagnoses of these patients were as follows: human parvovirus B19 infection (30.6%), transient aplastic crisis (16.7%), arthritis (8.3%) and acute hepatitis (4.1%). Symptoms of each of the four phases of the infection occurred in various combinations with the exception of the monophase of cheek exanthema. This occurred without the presence of other symptoms in some cases. Leading symptoms and signs were exanthema (in 74.6% of cases), haematological disorders (in 69% of cases), fever (in 54.9% of cases) and arthritis (in 33.8% of cases). Several atypical dermatological symptoms were also observed. Acute arthritis without exanthema was noted in 8 patients. Of the 72 patients with proven human parvovirus B19 infection there were 7 pregnant women, and one of them had hydrops foetalis resulting spontaneous abortion. In 16 patients (22.5%) human parvovirus B19 IgG was undetectable despite an optimal time for testing.
CONCLUSION: The observations of this study may contribute to a better recognition of clinical symptoms of human parvovirus B19 infection.
Ilona Mihály; András Trethon; Zsuzsanna Arányi; Adrienne Lukács; Tímea Kolozsi; Gyula Prinz; Anikó Marosi; Nóra Lovas; Ilona Sarolta Dobner; Géza Prinz; Zsuzsanna Szalai; Tamás Pék
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Orvosi hetilap     Volume:  153     ISSN:  0030-6002     ISO Abbreviation:  Orv Hetil     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-03     Completed Date:  2013-02-15     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  0376412     Medline TA:  Orv Hetil     Country:  Hungary    
Other Details:
Languages:  hun     Pagination:  1948-57     Citation Subset:  IM    
Vernacular Title:
A 2011. évi B19 humán parvovírus-fertőzésekről szerzett tapasztalatok.
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MeSH Terms
Abortion, Spontaneous / virology
Acute Disease
Antibodies, Viral / isolation & purification
Arthritis / diagnosis*,  epidemiology,  virology
Child, Preschool
Diagnosis, Differential
Erythema Infectiosum / diagnosis*,  epidemiology
Hungary / epidemiology
Immunoenzyme Techniques
Immunoglobulin G / blood
Immunoglobulin M / blood
Medical Records
Middle Aged
Parvoviridae Infections / complications,  diagnosis*,  epidemiology,  physiopathology,  virology
Parvovirus B19, Human / immunology,  isolation & purification*,  pathogenicity
Pregnancy Complications, Infectious / diagnosis*,  epidemiology,  virology
Retrospective Studies
Reg. No./Substance:
0/Antibodies, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M

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