Document Detail


Observations on the different calcium metabolic patterns in sarcoidosis. A metabolic and kinetic study.
MedLine Citation:
PMID:  983804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Combined calcium balance and 47Ca turnover studies in sarcoidosis (4 patients) and vitamin D intoxication (1 patient) disclosed three different patterns of calcium metabolism. On patient with sarcoidosis had a normal metabolism of calcium, and two patients presented the usual pattern of intestinal hyperabsorption, hypercalcemia, and hypercalciuria. The fourth patient with sarcoidosis and the patient with vitamin D intoxication, both studied during spontaneous remissions, presented the third pattern. The main features here were hypercalcemia despite normal intestinal absorption of calcium, enlarged exchangeable calcium pool, accelerated accretion and resorption rates, hypercalciuria, and a distinctly negative calcium balance. This pattern of remission seems to represent a mobilization of extraosseous or metastatic calcifications, rather than a resorption of bone calcium.
Authors:
I Hornum; I Transbol
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  200     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1976  
Date Detail:
Created Date:  1976-12-30     Completed Date:  1976-12-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  341-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Calcium / metabolism*
Cortisone / diagnostic use
Female
Glomerular Filtration Rate
Humans
Hypercalcemia / etiology
Intestinal Absorption
Kinetics
Male
Middle Aged
Sarcoidosis / diagnosis,  diet therapy,  metabolism*
Vitamin D / metabolism
Chemical
Reg. No./Substance:
1406-16-2/Vitamin D; 53-06-5/Cortisone; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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