Document Detail


Observations on coronary collateral communications and the control of flow in the coronary circulation of the dog.
MedLine Citation:
PMID:  5499785     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Pressure was measured in the small arterial anastomosing branches of the coronary vascular network. The mean value was 30 mm Hg not significantly different from the mean value of 33 mm Hg for peripheral coronary pressure measured distal to a ligature on the anterior descending branch of the left coronary artery. Evidence was adduced to show that either the anterior descending or the circumflex artery had the capacity to maintain network pressure at levels adequate for tissue perfusion.2. The network has both capacity and compliance. Filling of the network compliance during systole probably accounts for the systolic phase of coronary flow. Flow through the microcirculation is probably entirely diastolic, the combined compliance of the aorta and large vessels together with the network provides the necessary reservoir, the potential energy indicated by diastolic pressure provides the perfusion pressure head.3. Resistance of vessels between the aorta and network cannula (pre-net) was approximately double that of the microcirculation (post-net). The smaller pre-network vessels are of the order 70 mum in diameter. Both pre- and post-network vessels are vaso-active and respond similarly to adrenaline and haemorrhage.
Authors:
R L Coulson; J Gryson; M Irvine
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of physiology     Volume:  208     ISSN:  0022-3751     ISO Abbreviation:  J. Physiol. (Lond.)     Publication Date:  1970 Jul 
Date Detail:
Created Date:  1971-03-31     Completed Date:  1971-03-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0266262     Medline TA:  J Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  563-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Aorta / physiology
Arteries
Blood Pressure
Collateral Circulation*
Coronary Vessels / drug effects,  physiology*,  physiopathology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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