Document Detail

Observations on colloid osmotic pressure, hematocrit, and plasma osmolality during cardiac arrest.
MedLine Citation:
PMID:  3931978     Owner:  NLM     Status:  MEDLINE    
A porcine model of cardiac arrest with irreversible electromechanical dissociation was associated with highly significant decreases in colloid osmotic pressure in the absence of increases in hematocrit during the initial half hour of CPR. Pulmonary edema was typically observed. These observations are best explained by increases in capillary permeability to plasma proteins. The progression of acidemia was remarkably slow; arterial blood pH remained normal for more than 16 min. Even though there was significant lactic acidosis, concurrent respiratory alkalosis during CPR accounted for the greatly delayed onset of acidemia. There was also an as-yet unexplained increase in plasma osmolality.
W G Grundler; M H Weil; J M Miller; E C Rackow
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  13     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-12-02     Completed Date:  1985-12-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  895-6     Citation Subset:  AIM; IM    
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MeSH Terms
Bicarbonates / blood
Blood Pressure
Carbon Dioxide / blood
Electrolytes / blood
Heart Arrest / blood,  physiopathology*,  therapy
Hydrogen-Ion Concentration
Osmolar Concentration
Reg. No./Substance:
0/Bicarbonates; 0/Electrolytes; 124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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