Document Detail

Observations at the interface of mutation research and regulatory policy.
MedLine Citation:
PMID:  12888105     Owner:  NLM     Status:  MEDLINE    
Between 1970 and 1975 developments in environmental mutagenesis proceeded with amazing speed. These developments were both structural and conceptual in nature. A new infrastructure was built and new concepts about how best to protect consumers from exposures to mutagens emerged. The internal dynamics within the Food and Drug Administration played an important role and is discussed with regard to modifications in testing protocols as well as changes in the overall approach used to protect consumers. It is clear that this exciting period in the early days of environmental mutagenesis has provided a base for growth and development of the field and continues to affect and guide future developments.
W Gary Flamm
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Publication Detail:
Type:  Historical Article; Journal Article    
Journal Detail:
Title:  Mutation research     Volume:  544     ISSN:  0027-5107     ISO Abbreviation:  Mutat. Res.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-07-30     Completed Date:  2003-10-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0400763     Medline TA:  Mutat Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1-7     Citation Subset:  IM    
4401 Sunset Drive, 32963, Vero Beach, FL , USA.
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MeSH Terms
Carcinogens, Environmental / standards
Food / standards
Government Regulation / history*
Health Policy / history*
History, 20th Century
Legislation, Drug / history
Legislation, Food / history
Mutagenicity Tests / history*,  methods
Toxicology / history,  methods
United States
United States Food and Drug Administration / history*
Reg. No./Substance:
0/Carcinogens, Environmental

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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