Document Detail


Observational study of buprenorphine treatment of opioid-dependent pregnant women in a family medicine residency: reports on maternal and infant outcomes.
MedLine Citation:
PMID:  21383220     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
METHODS: This study consists of a retrospective case series of 23 infants born to 22 pregnant women who were dependent on opioids and who were treated with buprenorphine during a 31-month period.
RESULTS: Thirty-five percent of infants (8 of 23) required treatment for NAS. There was no significant relationship between maternal dose of buprenorphine and birth weight, NAS severity (ie, peak NAS score), or time to first peak NAS score. Infants born to tobacco users had a significantly lower birth weight (P = .0136) than infants born to nonusers. Seventy percent of infants (16 of 23) were breastfeeding at the time of discharge from the hospital.
CONCLUSIONS: The observations made in this case series are consistent with data previously reported in the literature. Infants in this study were more likely to be breastfed than those previously described by others, but further analysis is necessary to determine whether this finding is significant.
Authors:
Alane O'Connor; William Alto; Katje Musgrave; Daniel Gibbons; Lalaine Llanto; Selma Holden; Jonathan Karnes
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Board of Family Medicine : JABFM     Volume:  24     ISSN:  1557-2625     ISO Abbreviation:  J Am Board Fam Med     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-03-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101256526     Medline TA:  J Am Board Fam Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  194-201     Citation Subset:  IM    
Affiliation:
the Maine Dartmouth Family Medicine Residency, Augusta.
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