| Observational study of buprenorphine treatment of opioid-dependent pregnant women in a family medicine residency: reports on maternal and infant outcomes. | |
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MedLine Citation:
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PMID: 21383220 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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METHODS: This study consists of a retrospective case series of 23 infants born to 22 pregnant women who were dependent on opioids and who were treated with buprenorphine during a 31-month period. RESULTS: Thirty-five percent of infants (8 of 23) required treatment for NAS. There was no significant relationship between maternal dose of buprenorphine and birth weight, NAS severity (ie, peak NAS score), or time to first peak NAS score. Infants born to tobacco users had a significantly lower birth weight (P = .0136) than infants born to nonusers. Seventy percent of infants (16 of 23) were breastfeeding at the time of discharge from the hospital. CONCLUSIONS: The observations made in this case series are consistent with data previously reported in the literature. Infants in this study were more likely to be breastfed than those previously described by others, but further analysis is necessary to determine whether this finding is significant. |
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Authors:
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Alane O'Connor; William Alto; Katje Musgrave; Daniel Gibbons; Lalaine Llanto; Selma Holden; Jonathan Karnes |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Board of Family Medicine : JABFM Volume: 24 ISSN: 1557-2625 ISO Abbreviation: J Am Board Fam Med Publication Date: 2011 Mar-Apr |
Date Detail:
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Created Date: 2011-03-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101256526 Medline TA: J Am Board Fam Med Country: United States |
Other Details:
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Languages: eng Pagination: 194-201 Citation Subset: IM |
Affiliation:
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the Maine Dartmouth Family Medicine Residency, Augusta. |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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