Document Detail

Observation of the selective staining of chromosomal DNA in dividing cells using a luminescent terbium(III) complex.
MedLine Citation:
PMID:  20309461     Owner:  NLM     Status:  MEDLINE    
The emission intensity of a monocationic Tb or Eu(III) complex of a bis(1-azaxanthone) ligand is enhanced in the presence of serum albumin; the lanthanide complex stains dividing cells, allowing visualisation of mitotic chromosomes.
Ga-Lai Law; Cornelia Man; David Parker; James W Walton
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-02
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  46     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-23     Completed Date:  2010-07-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  2391-3     Citation Subset:  IM    
Department of Chemistry, Durham University, South Road, Durham, UK DH1 3LE.
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MeSH Terms
Coordination Complexes / chemistry*
DNA / chemistry*
Europium / chemistry
Hela Cells
Microscopy, Fluorescence
Terbium / chemistry*
Reg. No./Substance:
0/Coordination Complexes; 0/Ligands; 7440-27-9/Terbium; 7440-53-1/Europium; 9007-49-2/DNA

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