Document Detail

Observation on the effects of Chinese medicine zhenxuanyin for improving cerebral blood flow in rats with cerebral ischemia.
MedLine Citation:
PMID:  10437217     Owner:  NLM     Status:  MEDLINE    
Zhenxuanyin [symbol: see text] is composed of pure Chinese medicinal herbs, such as gastrodia tuber, poria cocos, ligusticum wallichii etc. 4-verssel occlusion (4VO) model rats were reperfused after 30 minutes' complete occlusion, and Zhenxuanyin was administered 3 times a day. 24 hours later, 123I-IMP uptake in the brain was evaluated as an index of cerebral blood flow (CBF). The results show that Zhenxuanyin (0.03 g/kg, 0.3 g/kg, 1 g/kg, or 3 g/kg a day) can greatly improve the blood flow in the main cerebral regions, and 0.3 g/kg can increase cerebral blood flow (CBF) to the normal level.
W Jingyi; M Yasuhiro; H Naoya; R C Seok; Y Yoshiharu; T Nagara; T Fumiko; M Shigeru; K Junji
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine     Volume:  17     ISSN:  0255-2922     ISO Abbreviation:  J Tradit Chin Med     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1999-09-10     Completed Date:  1999-09-10     Revised Date:  2010-11-03    
Medline Journal Info:
Nlm Unique ID:  8211546     Medline TA:  J Tradit Chin Med     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  299-303     Citation Subset:  IM    
Department of Nuclear Medicine, Faculty of Medicine, Kyoto University, Japan.
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MeSH Terms
Blood Flow Velocity / drug effects
Cerebrovascular Circulation / drug effects*
Dose-Response Relationship, Drug
Drugs, Chinese Herbal / pharmacology*
Iofetamine / diagnostic use
Rats, Wistar
Vertebrobasilar Insufficiency / physiopathology*
Reg. No./Substance:
0/Drugs, Chinese Herbal; 95896-48-3/Iofetamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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