| Objectively-measured and self-reported physical activity and fitness in relation to inflammatory markers in European adolescents: The HELENA Study. | |
| | |
MedLine Citation:
|
PMID: 22265274 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVE: Atherogenesis involves an inflammatory process that occurs early in life even though clinical symptoms are not observed until adulthood. Two important protective factors for low-grade inflammation may be physical activity (PA) and fitness. We examined the independent associations of objective and subjective measurements of PA and fitness with low-grade inflammation in European adolescents. METHODS: A total of 1045 adolescents, aged from 12.5 to 17.5 years old from 10 European cities, were selected from the HELENA-Cross-Sectional Study. Objectively-measured and self-reported PA variables were obtained by accelerometry and the International PA Questionnaire for Adolescents, respectively. Overall, cardiorespiratory, muscular and motor fitness variables were assessed by standardized field-based fitness tests and the International Fitness Scale. C-reactive protein (CRP), complement factors 3 (C3) and 4 (C4), interleukin-6 and TNF-α inflammatory markers were measured. RESULTS: Objectively-measured vigorous PA was inversely associated with C3 (β=-0.094, P=0.021) but it did not remain significant after any objective fitness indicator was included in the model. Other objectively measured or self-reported assessments of PA were not significantly associated with inflammatory markers. All objective measures of fitness were inversely associated with CRP, C3 and C4, whereas only self-reported motor fitness remained significantly associated with C3, C4 and TNF-α. All these observations were independent of age, sex, city and body mass index or waist circumference. CONCLUSION: High PA in adolescence may play an indirect role on lessening low-grade inflammation through improvements in fitness. |
| | |
Authors:
|
David Martinez-Gomez; Sonia Gomez-Martinez; Jonatan R Ruiz; Ligia Esperanza Diaz; Francisco B Ortega; Kurt Widhalm; Magdalena Cuenca-Garcia; Yannis Manios; Tineke De Vriendt; Denes Molnar; Inge Huybrechts; Christina Breidenassel; Frederic Gottrand; Maria Plada; Sara Moreno; Marika Ferrari; Luis A Moreno; Michael Sjöström; Ascension Marcos; |
Related Documents
:
|
1605814 - Older driver population and crash involvement trends, 1974-1988. 18018434 - Breath-hold time during cold water immersion: effects of habituation with psychological... 2963374 - Effect of fork-lift truck driving on low-back trouble. 2872834 - Heavy drinking among norwegian male drunken drivers: a study of gamma-glutamyltransferase. 21774944 - Mechanistic studies on the formation of silver nanowires by a hydrothermal method. 15699054 - Television and music video exposure and adolescent alcohol use while going out. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-29 |
Journal Detail:
|
Title: Atherosclerosis Volume: - ISSN: 1879-1484 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2012-1-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0242543 Medline TA: Atherosclerosis Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Immunonutrition Research Group, Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council, Calle José Antonio Novais 10, 28040 Madrid, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Correlation of peripheral Th17 cells and Th17-associated cytokines to the severity of carotid artery...
Next Document: Dietary fats and dietary cholesterol and risk of stroke in women.