| Objective and subjective measurements of cutaneous inflammation after a novel hyaluronic acid injection. | |
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MedLine Citation:
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PMID: 18547174 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hyaluronic acid (HA) dermal fillers are commonly used to minimize the appearance of facial lines and wrinkles. However, after the injection of HA, there is normally a mild inflammatory reaction. All published studies to date have measured this unwanted side effect by subjective means only. OBJECTIVE: The primary objective was to determine the magnitude and duration of the inflammation induced by injection of a novel HA using objective and subjective means. MATERIALS AND METHODS: The study was an open study in 25 normal volunteer subjects. All subjects had a single injection and were assessed objectively using an erythema meter and infrared thermometer and subjectively using established clinical scales. RESULTS: The erythema meter and the infrared thermometer objectively measured the mild cutaneous inflammation, which was transitory in nature. These objective measurements correlated well with the subjective clinical scores. CONCLUSIONS: The results of this study show that the erythema meter and the infrared thermometer are effective tools to objectively measure mild inflammation post-HA injection. |
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Authors:
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Harryono Judodihardjo; Peter Dykes |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Volume: 34 Suppl 1 ISSN: 1524-4725 ISO Abbreviation: Dermatol Surg Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-12 Completed Date: 2008-08-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9504371 Medline TA: Dermatol Surg Country: United States |
Other Details:
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Languages: eng Pagination: S110-4 Citation Subset: IM |
Affiliation:
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The Cellite Clinic Ltd, Cardiff, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biocompatible Materials / administration & dosage, adverse effects* Cosmetic Techniques / adverse effects* Edema / chemically induced, diagnosis Erythema / chemically induced, diagnosis Face Female Humans Hyaluronic Acid / administration & dosage, adverse effects* Inflammation / chemically induced, diagnosis* Injections, Intradermal Middle Aged Pain / chemically induced, diagnosis Pain Measurement Skin / pathology Skin Aging Skin Temperature Spectrophotometry Statistics, Nonparametric Thermography |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 9004-61-9/Hyaluronic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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