Document Detail

Objective measurement of motor disability in Parkinson's disease.
MedLine Citation:
PMID:  2618595     Owner:  NLM     Status:  MEDLINE    
A kinesiological analysis of complex movement performance was carried out in patients with Parkinson's disease, and in healthy subjects of different ages, with a computer-assisted optoelectronic camera system. A lifting movement entailing simultaneous coordination of rising, walking some steps and a goal-directed manual movement, the PLM test, was used. Speed reduction through normal aging was greatest at higher ages, where the coordination deficits were also most prominent. The increased movement time in parkinsonian patients was due both to deficient simultaneous coordination of postural, locomotor and manual movement phases, and to varying increases in phase durations. It was possible to determine postural, locomotor and manual disability profiles quantitatively, in terms of the relative phase time values. The presented documentation of parkinsonian disability and single-dose effects of l-dopa indicates that the technique is applicable in the objective assessment of disability and pharmacotherapeutic efficacy.
G Steg; P E Ingvarsson; B Johnels; M Valls; M Thorselius
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurologica Scandinavica. Supplementum     Volume:  126     ISSN:  0065-1427     ISO Abbreviation:  Acta Neurol. Scand., Suppl.c     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-05     Completed Date:  1990-03-05     Revised Date:  2012-05-07    
Medline Journal Info:
Nlm Unique ID:  0370337     Medline TA:  Acta Neurol Scand Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  67-75     Citation Subset:  IM    
Department of Neurology, University of Gothenburg, Sweden.
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MeSH Terms
Aged, 80 and over
Locomotion / physiology
Motor Activity / physiology
Movement / physiology*
Parkinson Disease / physiopathology*
Posture / physiology

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