Document Detail


Obesity and weight loss in the treatment and prevention of osteoarthritis.
MedLine Citation:
PMID:  22632704     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Obesity is associated with an increasing prevalence of musculoskeletal complaints and pain. Obesity is a major risk factor for osteoarthritis (OA), and pain can manifest in load-bearing and nonload-bearing joints. The lumbar spine and the knee are 2 primary sites for pain onset in the obese patient. Irrespective of the weight loss method, reduction of body fat can lower the mechanical and inflammatory stressors that contribute to OA. Single or combined methods of weight loss including exercise, dietary modification, medications, and bariatric surgery are associated with lower joint pain and increased physical function. Methods of weight loss or maintenance in early years may reduce the life exposure of joints to the obesity induced stressors on load bearing joints.
Authors:
Heather K Vincent; Kendrick Heywood; Jacob Connelly; Robert W Hurley
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  PM & R : the journal of injury, function, and rehabilitation     Volume:  4     ISSN:  1934-1563     ISO Abbreviation:  PM R     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-10-09     Revised Date:  2013-06-24    
Medline Journal Info:
Nlm Unique ID:  101491319     Medline TA:  PM R     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S59-67     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Orthopaedics and Rehabilitation, Division of Research, University of Florida, UF Orthopaedics and Sports Medicine Institute, PO Box 112727, Gainesville, FL 32611, USA. vincehk@ortho.ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Biomechanics
Diet
Exercise Therapy*
Gait
Humans
Muscle Strength
Obesity / epidemiology*
Osteoarthritis / epidemiology*,  physiopathology,  prevention & control,  rehabilitation,  therapy*
Risk Factors
Grant Support
ID/Acronym/Agency:
#AR057552-01A1/AR/NIAMS NIH HHS; #AR059786/AR/NIAMS NIH HHS; #RO3 AR057552-01A1/AR/NIAMS NIH HHS; R03 AR057552/AR/NIAMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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