| Obesity-related hypertension: role of the sympathetic nervous system, insulin, and leptin. | |
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MedLine Citation:
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PMID: 11884266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heightened sympathetic nervous system activity, hyperinsulinemia, insulin resistance, and hyperleptinemia contribute to obesity-related hypertension. However, the precise mechanism and sequence of events in this pathophysiologic event have not been clarified. This review concentrates on studies helping to clarify the mechanisms of blood pressure elevation associated with weight change, concentrating on the temporal changes in neuroendocrine factors that are known to control energy metabolism and blood pressure. A better understanding of the pathophysiologic mechanisms of obesity-related hypertension may help in prevention, treatment, and slowing of the cardiovascular complications of obesity. |
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Authors:
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Kazuko Masuo |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current hypertension reports Volume: 4 ISSN: 1522-6417 ISO Abbreviation: Curr. Hypertens. Rep. Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-03-08 Completed Date: 2002-05-01 Revised Date: 2006-07-12 |
Medline Journal Info:
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Nlm Unique ID: 100888982 Medline TA: Curr Hypertens Rep Country: United States |
Other Details:
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Languages: eng Pagination: 112-8 Citation Subset: IM |
Affiliation:
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Department of Geriatric Medicine, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita City, Osaka 565-0871 Japan. kazukom7@dream.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure
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physiology Body Weight / physiology Exercise / physiology Food Habits / physiology Humans Hypertension / complications*, physiopathology Insulin / physiology Japan / epidemiology Leptin / physiology Neurotransmitter Agents / physiology Obesity / complications*, physiopathology Risk Factors Sweden / epidemiology Sympathetic Nervous System / physiology |
| Chemical | |
Reg. No./Substance:
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0/Leptin; 0/Neurotransmitter Agents; 11061-68-0/Insulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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