| Obesity and insulin resistance in women with polycystic ovary syndrome. | |
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MedLine Citation:
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PMID: 20500115 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective. To evaluate the impact of obesity and various phenotypes of polycystic ovary syndrome (PCOS) on the insulin sensitivity index (ISI) and insulin resistance (IR). Methods. ISI and IR from 273 women in four phenotypes of PCOS and control groups were evaluated retrospectively. Results. The ISI and the percentage of IR were not significantly different among discrete phenotypes of PCOS groups and normal controls. Obesity (OR = 14.0, 95% CI (Confidence Interval), 7.5-26.5) results in a higher risk for developing insulin resistance than hyperandrogenemia (OR = 2.1, 1.3-3.6), oligomenorrhea (OR = 1.8, 1.0-3.3) and polycystic ovary morphology (PCOM) (OR = 1.4, 0.8-2.7). Conclusion. The ISI did not differ significantly among the various phenotypes of PCOS. In comparison with hyperandrogenemia, chronic anovulation, and PCOM, obesity was the dominant risk factor in determining insulin resistance in women with PCOS. |
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Authors:
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Hsu Chun-Sen; Wu Chien-Hua; Chiu Wan-Chun; Lee Ching-Tzu; Chang Chun-Jen; Hsu Ming-I |
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Publication Detail:
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Type: Journal Article Date: 2010-05-26 |
Journal Detail:
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Title: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Volume: 27 ISSN: 1473-0766 ISO Abbreviation: Gynecol. Endocrinol. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8807913 Medline TA: Gynecol Endocrinol Country: England |
Other Details:
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Languages: eng Pagination: 300-6 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Taipei Medical University, Wan Fang Hospital, Taipei, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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