| Obesity and cervical ripening failure risk. | |
| | |
MedLine Citation:
|
PMID: 21574901 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Objective. To estimate the impact of obesity on cervical ripening with prostaglandin E2 (PGE2). Materials and method. A retrospective study compared the cervical ripening efficiency of PGE2 on patients with BMI above 30 kg/m(2) and normal weight patients with BMI between 20 kg/m(2) and 25 kg/m(2). In case of a Bishop score (≤3), a dinoprostone tampon was used over 12 h. In case of a Bishop score (4;6), a dinoprostone gel was used over 6 h. Failure of first cervical ripening attempt was defined, as the persistence of a Bishop score <6, 12 h after dinoprostone tampon or 6 h after dinoprostone gel. Results. Ninety-five obese patients were matched according to parity to 190 non-obese patients. The failure rate of the first attempt at cervical ripening was significantly higher (P = 0.0016) among obese patients (53.7%) as compared to patients with a BMI in between 20 and 25 (34.2%). After multivariate analysis BMI ≥ 30 (OR = 2.32 (1.47-4.00), P = 0.0019), parity ≤2 (OR = 2.50 (1.20-5.26) P = 0.0137), and the Bishop score ≤3 (OR = 2.62 (1.45-4.72), P = 0.0014) were significantly and independently associated to prostaglandin ripening failure. Conclusion. Obesity seems to be associated to lower E2 prostaglandin sensitivity. |
| | |
Authors:
|
Tristan Gauthier; Sophie Mazeau; François Dalmay; Jean-Luc Eyraud; Cyril Catalan; Benoit Marin; Yves Aubard |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-17 |
Journal Detail:
|
Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: - ISSN: 1476-4954 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Gynaecology and obstetrics, Hospital Mère Enfant, CHU Dupuytren, av Larrey 87000 Limoges, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ionized calcium levels in umbilical cord blood of women with preeclampsia and normotensive pregnanci...
Next Document: Scan the fetal heart by real-time three-dimensional echocardiography with live xPlane imaging.