Document Detail


Obesity and its impact on transplantation and alloimmunity.
MedLine Citation:
PMID:  23416683     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Obesity has become an increasing problem in healthcare worldwide with far-reaching consequences. More obese patients with irreversible end-stage organ failure undergo organ transplantation, and organs from obese donors are more frequently used. A growing body of evidence suggests more frequent postoperative complications and inferior patient and graft survival linked to obesity. More recently, adipose tissue has been linked to chronic inflammatory processes potentially impacting alloimmune responses and graft quality.
Authors:
Timm Heinbokel; Bernhard Floerchinger; Andreas Schmiderer; Karoline Edtinger; Guangxiang Liu; Abdallah Elkhal; Stefan G Tullius
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Transplantation     Volume:  96     ISSN:  1534-6080     ISO Abbreviation:  Transplantation     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-28     Completed Date:  2013-09-03     Revised Date:  2014-01-03    
Medline Journal Info:
Nlm Unique ID:  0132144     Medline TA:  Transplantation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Graft Rejection / epidemiology,  immunology*
Graft Survival / immunology
Humans
Isoantibodies / immunology*
Obesity / epidemiology,  immunology*
Prevalence
Transplantation*
Transplantation Immunology*
Grant Support
ID/Acronym/Agency:
AG039449/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Isoantibodies
Comments/Corrections
Comment In:
Transplantation. 2013 Nov 27;96(10):e72-3   [PMID:  24247904 ]
Transplantation. 2013 Nov 27;96(10):e71-2   [PMID:  24247903 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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