Document Detail

The O.M.G.E. Multinational Inflammatory Bowel Disease Survey 1976-1982. A further report on 2,657 cases.
MedLine Citation:
PMID:  6379849     Owner:  NLM     Status:  MEDLINE    
This presentation describes the progress during 1978-1982 of the O.M.G.E. Multinational Survey of patients with inflammatory bowel disease. After a brief description of the study design and protocol, and review of results up to 1978, the status of the survey in 1982 is presented. In all, 35 centres contributed 2,657 cases at that time; data collection being meticulous via previously designed proformata. Diagnostic criteria are next discussed. Little change between 1978 and 1982 is noted, with wide variation in the UC/CD ratio for individual centres, but continuing evidence of a congruence of diagnostic thought, now codified into a simple (and recommended) O.M.G.E. Scoring System. Patients seen prior to 1978 were reviewed in 1982. Where attempted, a follow-up of over 90% was achieved, usually more than four years after the original presentation. Interesting data resulted. The stability of diagnosis was high, only 3.4% of patient diagnoses changing between 1978 and 1982. The mortality of Crohn's disease patients, usually unrelated to surgery, was higher than that of ulcerative colitis patents, and the cancer risk identical in the two groups. Most patients were well at review; but--though asymptomatic--were usually on prophylactice therapy, most commonly with salazopyrine. Finally, problems in assessing severity and activity of disease are discussed, and joint studies between O.M.G.W. and the newly formed International Organisation for the Study of I.B.D. described. As regards Crohn's disease, several 'indices of activity' already exist; when tested on a set of 200 O.M.G.E. patients, indices did not correlate well with each other, or with patient prognosis. Further studies are suggested during 1982-1986.
J Myren; I A Bouchier; G Watkinson; A Softley; S E Clamp; F T de Dombal
Related Documents :
3067339 - Olsalazine in the treatment of active ulcerative colitis: a placebo controlled clinical...
15542519 - Clinical and subclinical intestinal inflammation assessed by the mucosal patch techniqu...
22880809 - Development of refractory ascites during amiodarone therapy in a hemodialysis patient w...
22527129 - Vascular dysfunction by myofibroblast activation in patients with idiopathic pulmonary ...
2495239 - Disturbed fibrinolysis in patients with inflammatory bowel disease. a study in blood pl...
22897169 - Haemodynamic effects of non-invasive ventilation in patients with obesity-hypoventilati...
6984629 - Trisomy 17p due to a t(5;17) (p15;p11) pat translocation.
23090369 - Epidemiological profile of patients with extra-articular manifestations of rheumatoid a...
2223379 - Bone scanning in patients with pleural effusion--experience in 76 cases.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology. Supplement     Volume:  95     ISSN:  0085-5928     ISO Abbreviation:  Scand. J. Gastroenterol. Suppl.     Publication Date:  1984  
Date Detail:
Created Date:  1984-08-27     Completed Date:  1984-08-27     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0437034     Medline TA:  Scand J Gastroenterol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  1-27     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Colitis, Ulcerative / diagnosis*,  epidemiology,  therapy
Crohn Disease / diagnosis*,  epidemiology,  therapy
Diagnosis, Computer-Assisted
Diagnosis, Differential
Follow-Up Studies
Longitudinal Studies
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Distortion of wax crowns.
Next Document:  The O.M.G.E. Acute Abdominal Pain Survey--progress report, 1982.