Document Detail

OCD behavior therapy before and after gamma ventral capsulotomy: Case report.
MedLine Citation:
PMID:  23057416     Owner:  NLM     Status:  Publisher    
We report the case of a patient requiring gamma ventral capsulotomy (GVC), a neurosurgical intervention to address severe refractory obsessive-compulsive disorder (OCD). GVC involves stereotactic lesions in the ventral anterior limb of the internal capsule and adjacent ventral striatum. This study details the course of an extinction-based behavioral therapy, namely exposure and response prevention (ERP). The patient experienced significant changes in motivation and ability to tolerate ERP post-surgery. Furthermore, he was better able to absorb and remember exposure sessions. GVC surgery may affect the neural mechanisms involved in the extinction learning process, the same process implicated in ERP treatment.
Christopher M Spofford; Nicole C R McLaughlin; Fred Penzel; Steven A Rasmussen; Benjamin D Greenberg
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-12
Journal Detail:
Title:  Neurocase     Volume:  -     ISSN:  1465-3656     ISO Abbreviation:  Neurocase     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9511374     Medline TA:  Neurocase     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
a Department of Psychiatry and Human Behavior , The Warren Alpert Medical School at Brown University , Providence , RI , USA.
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