Document Detail

Nutritional support for the infant's immune system.
MedLine Citation:
PMID:  17867369     Owner:  NLM     Status:  MEDLINE    
Newborn babies possess a functional but immature immune system as a defense against a world teeming with microorganisms. Breast milk contains a number of biological, active compounds that support the infant's immune system. These include secretory immunoglobulin A (IgA), which confers specific protection against enteric pathogens, as well as numerous other immunological, active ingredients. A number of these ingredients can be used as supplements for infant formulas based on cow's milk. Here, the strength of evidence regarding the immune-stimulating effects of selected minerals, vitamins, fatty acids, pre- and probiotics, and nucleotides is reviewed. An assessment of how these ingredients are used in infant-formula products currently available on the market is also presented.
Laetitia Niers; Marianne Stasse-Wolthuis; Frans M Rombouts; Ger T Rijkers
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Nutrition reviews     Volume:  65     ISSN:  0029-6643     ISO Abbreviation:  Nutr. Rev.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-17     Completed Date:  2007-10-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376405     Medline TA:  Nutr Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  347-60     Citation Subset:  IM    
Department of Pediatrics, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands.
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MeSH Terms
Immune System / immunology*,  physiology
Immunity, Mucosal / immunology,  physiology
Immunoglobulin A, Secretory / immunology
Infant Formula
Infant Nutritional Physiological Phenomena / immunology*
Infant, Newborn / immunology*
Intestinal Mucosa / immunology,  physiology
Milk, Human / immunology*
Nucleotides / administration & dosage,  immunology
Reg. No./Substance:
0/Immunoglobulin A, Secretory; 0/Nucleotides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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