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Nutritional support in patients with acute pancreatitis.
MedLine Citation:
PMID:  22202015     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Pancreatitis is a diffuse systemic immuno-inflammatory response to a localized process of auto-digestion within the pancreatic gland, caused by premature activation of proteolytic digestive enzymes. According to the ATLANTA criteria (1992) we recognized a mild and a severe acute pancreatitis (SAP ) . Mortality rate in SAP account up to the 20 percent and most complications and deaths are due to an inflammatory immune response to pancreatic necrosis and/or infection. Patients affected by SAP rapidly incur accelerated catabolism and thus nutritional support is essential, especially in the earliest period of the disease. Recent observations show that the route of nutritional support may also affect disease severity and its course. In this view several important questions about nutritional support need to be addressed : indication , timing, enteral vs parenteral and composition . With this review we analyze the state-of-the-art and we present a decisional flow chart to better manage the nutritional support in SAP.
Authors:
Giuseppe Piccinni; Mario Testini; Anna Angrisano; Germana Lissidini; Angela Gurrado; Riccardo Memeo; Francesco Basile; Antonio Biondi
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Publication Detail:
Type:  Journal Article     Date:  2012-01-01
Journal Detail:
Title:  Frontiers in bioscience (Elite edition)     Volume:  4     ISSN:  1945-0508     ISO Abbreviation:  Front Biosci (Elite Ed)     Publication Date:  2012  
Date Detail:
Created Date:  2011-12-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485240     Medline TA:  Front Biosci (Elite Ed)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1999-2006     Citation Subset:  IM    
Affiliation:
Section of General and Oncologic Surgery, Department of Biological Sciences and Human Oncology , University Medical School of Bari, Italy.
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