Document Detail

Nutritional status and psychometric test scores in cognitively impaired elders.
MedLine Citation:
PMID:  2735676     Owner:  NLM     Status:  MEDLINE    
In a pilot study, we compared dietary and biochemical status for vitamin B1, B2, B12, and C and folate, iron, and protein in CI and CN elders grouped by MMSE scores. Biochemical evaluation of folate and B12 status was continued beyond the preliminary study. Intakes of all nutrients except folate exceeded 66% of the RDA. There were no significant differences among MMSE groups for dietary intake or biochemical values. Transketolase activity increased with degree of impairment, whereas measures for the other vitamins declined. Low or deficient LAA levels were found in 33% of all elders. Folate and B12 deficiencies, respectively, were found in 11% (12/109) and 4% (10/254) of the population. Very low values for serum B12 (less than 250 pg/ml) existed in 15% (37/254) of the subjects (31 CI; 7 CN). Moderately impaired elders (MMSE = 15-20) who used multivitamin supplements had RBC folate (p less than .003) and serum B12 (p less than .02) levels higher than those of subjects who did not use supplements.
A A Spindler; M A Renvall
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  561     ISSN:  0077-8923     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  1989  
Date Detail:
Created Date:  1989-07-27     Completed Date:  1989-07-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  167-77     Citation Subset:  IM    
School of Family Studies and Consumer Sciences, San Diego State University, California 92182.
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MeSH Terms
Aged, 80 and over
Avitaminosis / metabolism
Blood Chemical Analysis
Cognition Disorders / physiopathology*
Energy Intake
Nutritional Status*
Vitamins / administration & dosage
Grant Support
Reg. No./Substance:

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