Document Detail


Nutritional status in patients with active inflammatory bowel disease: prevalence of malnutrition and methods for routine nutritional assessment.
MedLine Citation:
PMID:  20603043     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND AIM: Malnutrition is a common feature of inflammatory bowel disease (IBD). There are numerous methods for the assessment of nutritional status, but the gold standard has not yet been established. The aims of the study were to estimate the prevalence of undernutrition and to evaluate methods for routine nutritional assessment of active IBD patients.
MATERIAL AND METHODS: Twenty-three patients with active Crohn disease, 53 patients with active ulcerative colitis and 30 controls were included in the study. The nutritional status was assessed by extensive anthropometric measurements, percentage of weight loss in the past 1-6 months and biochemical markers of nutrition.
RESULTS: All investigated nutritional parameters were significantly different in IBD patients compared to control subjects, except MCV, tryglicerides and serum total protein level. Serum albumin level and body mass index (BMI) were the most predictive parameters of malnutrition. According to different assessment methods the prevalence of undernutrition and severe undernutrition in patients with active IBD were 25.0%-69.7% and 1.3%-31.6%, respectively, while in the control subjects no abnormalities have been detected. There was no statistically significant difference of nutritional parameters between UC and CD patients except lower mid-arm muscle circumference in UC group.
CONCLUSIONS: Malnutrition is common in IBD patients. BMI and serum albumin are simple and convenient methods for the assessment of the nutritional status in IBD patients. Further studies with larger group of patients are necessary to elucidate the prevalence of malnutrition and the most accurate assessment methods in IBD patients.
Authors:
Dragana D Mijac; Goran L J Janković; Jagoda Jorga; Miodrag N Krstić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of internal medicine     Volume:  21     ISSN:  1879-0828     ISO Abbreviation:  Eur. J. Intern. Med.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-06     Completed Date:  2010-11-09     Revised Date:  2011-02-04    
Medline Journal Info:
Nlm Unique ID:  9003220     Medline TA:  Eur J Intern Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  315-9     Citation Subset:  IM    
Affiliation:
Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, Serbia. dmijac@eunet.rs
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Blood Proteins / analysis
Case-Control Studies
Colitis, Ulcerative / complications
Crohn Disease / complications
Female
Humans
Inflammatory Bowel Diseases / complications*
Male
Malnutrition / diagnosis,  epidemiology,  etiology*
Middle Aged
Nutrition Assessment*
Nutritional Status / physiology*
Prevalence
Regression Analysis
Statistics, Nonparametric
Triglycerides / blood
Weight Loss / physiology
Young Adult
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Triglycerides
Comments/Corrections
Comment In:
Eur J Intern Med. 2011 Feb;22(1):13-5   [PMID:  21238886 ]

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