Document Detail

Nutritional risk factors in esophageal cancer.
MedLine Citation:
PMID:  11273469     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The present case-control study was undertaken with the objective to study the nutritional risk factors associated with esophageal cancer. METHODOLOGY: One hundred and fifty diagnosed esophageal cancer patients and an equal number of healthy individuals constituted the patient and control groups, respectively. Dietary consumption pattern during the preceding 20 years prior to the diagnosis of esophageal cancer was assessed utilising the standard food frequency questionnaire method. Information on alcohol consumption, smoking habits, chewing of betel leaf with tobacco was also collected. RESULTS: Multivariate analysis revealed that the risk of esophageal cancer was 7.81 times (p < 0.01) higher with daily consumption of alcohol. The risk increased to 3.16 times (p < 0.01) with the daily habit of chewing of betel leaf with tobacco. Nearly a two fold risk was observed when the consumption of "other vegetables" was less than four times per week. A 1.95 times (p < 0.01) increase in risk was observed with the daily habit of bidi smoking. CONCLUSION: Cancers in general are multifactorial in origin, and several environmental interactions are possible. It is not easy to quantify the contribution of diet to cancer risk. However, the results of the present study suggested that nutritional factors do play a role.
D Nayar; U Kapil; Y K Joshi; K R Sundaram; S P Srivastava; N K Shukla; R K Tandon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  48     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2001-03-01     Completed Date:  2001-04-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  781-7     Citation Subset:  IM    
Department of Human Nutrition and Institute of Rotary Cancer, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029.
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MeSH Terms
Alcohol Drinking / adverse effects
Areca / adverse effects
Esophageal Neoplasms / etiology*,  prevention & control
Food Habits*
Middle Aged
Plants, Medicinal
Risk Factors
Smoking / adverse effects

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