| Nutritional rehabilitation in Bangladesh--the importance of zinc. | |
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MedLine Citation:
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PMID: 3132034 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Our aim was to investigate whether zinc deficiency becomes apparent during nutritional rehabilitation and limits the rate of weight gain. Twenty-five severely malnourished children, who were admitted to the Children's Nutrition Unit in Bangladesh, were alternately allocated to two groups. Their mean dietary Zn intake was 3.7 mg/d and mean caloric intake greater than 150 kcal.kg-1.d-1; one group received a daily Zn supplement of 50 mg for 2 wk. During the first week, weight gain was similar in the two groups, but during the second week, weight gain was 73% more in the Zn-supplemented group (8.83 +/- 1.56 vs 5.09 +/- 1.62 g.kg-1.d-1). The 95% confidence limits were 0.88 less to 8.36 g.kg-1.d-1 more gain in children receiving Zn supplements. The results strongly suggest that Zn supplements are beneficial to severely malnourished children during nutritional rehabilitation. Polymorphonuclear (PMN) cell Zn increased in the group receiving Zn supplements (p less than 0.001), confirming that the Zn content of PMN cells reflects available Zn. |
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Authors:
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K Simmer; S Khanum; L Carlsson; R P Thompson |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 47 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 1988 Jun |
Date Detail:
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Created Date: 1988-07-08 Completed Date: 1988-07-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1036-40 Citation Subset: AIM; IM |
Affiliation:
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St. Thomas' Hospital, London. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bangladesh Body Weight Child Child, Preschool Ferritins / blood Hematocrit Humans Infant Kwashiorkor / therapy Neutrophils / metabolism Nutrition Disorders / diet therapy*, drug therapy, rehabilitation Protein-Energy Malnutrition / therapy Vitamin A / blood Vitamin E / blood Zinc / administration & dosage, blood, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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11103-57-4/Vitamin A; 1406-18-4/Vitamin E; 7440-66-6/Zinc; 9007-73-2/Ferritins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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