Document Detail


Nutritional intervention in uremia--myth or reality?
MedLine Citation:
PMID:  20797568     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nutritional intervention in uremia, specifically the restricted protein diet, has been under debate for decades. The results of various clinical trials have not been concordant, as some studies have reported positive effects of the low-protein diets, whereas others have shown no benefit. Recently published data show that the restricted protein diets seem to be effective and safe in ameliorating nitrogen waste products retention and the disturbances in acid-base and calcium-phosphorus metabolism, and in delaying the initiation of renal replacement therapy (RRT), without any deleterious effect on the nutritional status of patients with chronic kidney disease. The nutritional support and particularly the supplemented very low protein diet could be a new link to the RRT-integrated care model. A possible delay in RRT initiation through nutrition could have a major economic effect, particularly in developing countries, where the dialysis facilities still do not meet the requirements. However, a careful selection of motivated patients who could benefit from such a diet, closer nutritional monitoring, and dietary counseling are required.
Authors:
Liliana Garneata; Gabriel Mircescu
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation     Volume:  20     ISSN:  1532-8503     ISO Abbreviation:  J Ren Nutr     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-27     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112938     Medline TA:  J Ren Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S31-4     Citation Subset:  IM    
Copyright Information:
Copyright 2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Affiliation:
Dr Carol Davila Teaching Hospital of Nephrology, Bucharest, Romania. lilianagarna@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Amino Acids, Essential / administration & dosage
Diet, Protein-Restricted* / adverse effects
Dietary Supplements
Humans
Kidney Failure, Chronic / prevention & control
Nutritional Support
Randomized Controlled Trials as Topic
Renal Replacement Therapy / economics
Uremia / diet therapy*
Chemical
Reg. No./Substance:
0/Amino Acids, Essential

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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