| Nutritional challenge in pseudo-obstruction: the bridge between motility and nutrition. | |
| | |
MedLine Citation:
|
PMID: 19300134 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Chronic intestinal pseudo-obstruction is a severe syndrome characterized by a profound derangement of the intestinal propulsive motility that resembles mechanical obstruction, in the absence of any mechanical obstruction. This syndrome represents one of the main causes of intestinal failure and is characterized by impairment of physical growth and development as well as by a high rate of morbidity and mortality. It may be idiopathic or secondary to a variety of diseases. Most cases are sporadic, even though familial forms with either dominant or recessive autosomal inheritance have been described. Based on histological features intestinal pseudo-obstruction is classified into 3 main groups: neuropathies, mesenchymopathies, and myopathies, according to the predominant involvement of enteric neurones, interstitial cells of Cajal, and smooth muscle cells, respectively. Treatment of intestinal pseudo-obstruction involves nutritional, pharmacological, and surgical therapies, but it is often frustrating and does not change the natural course in the majority of cases. The nutritional management has a crucial importance in pediatric age and involves the administration of special formulae, the enteral delivery of nutrients, by a nasogastric tube, percutaneous gastrostomy, or jejunostomy. In the most severe cases, parenteral nutrition becomes mandatory in order to satisfy nutritional requirements and manage appropriately obstructive episodes. |
| | |
Authors:
|
Salvatore Cucchiara; Osvaldo Borrelli |
Related Documents
:
|
20097684 - Haemodynamic effects of acute intravenous metoprolol in apical ballooning syndrome with... 6154514 - Rhinitis medicamentosa. 2888844 - Gastrointestinal manifestations of sipple syndrome in children. 8176604 - Congenital high airway obstruction syndrome (chaos): a potential for perinatal interven... 3785884 - Kabuki make-up syndrome in a caucasian. 6477224 - Chédiak-higashi syndrome. neurologic appearance. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of pediatric gastroenterology and nutrition Volume: 48 Suppl 2 ISSN: 1536-4801 ISO Abbreviation: J. Pediatr. Gastroenterol. Nutr. Publication Date: 2009 Apr |
Date Detail:
|
Created Date: 2009-03-20 Completed Date: 2009-07-29 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8211545 Medline TA: J Pediatr Gastroenterol Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: S83-5 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Gastroenterology Service, Sapienza University of Rome, Rome, Italy. salvatore.cucchiara@uniroma1.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Gastrointestinal Motility Humans Intestinal Pseudo-Obstruction / therapy* Nutritional Support* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Congenital anorectal malformations: anything new?
Next Document: Nutritional aspects in inflammatory bowel disease.