Document Detail

Nutrition for the respiratory insufficient patient.
MedLine Citation:
PMID:  2508653     Owner:  NLM     Status:  MEDLINE    
Malnutrition is fairly common in patients with chronic obstructive pulmonary disease, the more severe the airway obstruction the more severe the nutritional status. The consequences of nutritional depletion on respiratory and immune systems are ventilatory compromise and susceptibility to infection. Diaphragm muscle mass and thickness is decreased in patients with COPD. This results in decreased maximum voluntary ventilation and diminished inspiratory pressure. Malnutrition is one of the causes of failure to wean in patients with respiratory failure. Malnutrition also has profound effects on cell-mediated immune response and humoral immunity with reduced levels of secretory IgA. In patients with COPD, colonization of respiratory tract bears a direct relationship with parameters of nutritional status. Patients with significant nutritional impairment have more tracheal cell bacteria adhered to and the tracheas were more frequently colonized by Pseudomonas species. The improvement of nutrition in these patients resulted in less bacterial cell binding to tracheal epithelial cells.
V Mohsenin; R Ferranti; J S Loke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The European respiratory journal. Supplement     Volume:  7     ISSN:  0904-1850     ISO Abbreviation:  Eur Respir J Suppl     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-11-27     Completed Date:  1989-11-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8910681     Medline TA:  Eur Respir J Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  663s-665s     Citation Subset:  IM    
Pulmonary Section, Yale University School of Medicine, New Haven, Connecticut 06510.
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MeSH Terms
Enteral Nutrition*
Lung Diseases, Obstructive / complications*,  immunology,  physiopathology
Nutrition Disorders / etiology,  immunology,  therapy*

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