| Nutrition and respiratory disease. | |
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MedLine Citation:
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PMID: 6426844 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Correlations between nutritional status and respiratory function, effects of nutritional substrates on respiration, and optimal nutritional support during respiratory failure are reviewed. Somatic protein depletion is common in patients with either acute respiratory failure or chronic obstructive pulmonary disease. The etiology of the malnutrition includes decreased nutrient intake, increased work of breathing, and increased metabolic rate caused by infections. Excessive administration of glucose or protein can have detrimental effects on respiratory status. Weaning patients from ventilators may be prolonged or even impossible secondary to increased carbon dioxide production in patients receiving high caloric loads of glucose. Excessive protein administration stimulates ventilatory drive and can be detrimental in patients who cannot increase their minute ventilation. Fat is the preferred substrate for energy in selected mechanically ventilated patients requiring total parenteral nutrition because it is oxidized at a lower respiratory quotient than glucose. Measurements of respiratory quotient, oxygen consumption, and carbon dioxide production can be useful in providing optimal nutritional support to the patient with respiratory compromise. |
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Authors:
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R O Brown; W D Heizer |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical pharmacy Volume: 3 ISSN: 0278-2677 ISO Abbreviation: Clin Pharm Publication Date: 1984 Mar-Apr |
Date Detail:
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Created Date: 1984-06-26 Completed Date: 1984-06-26 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8207437 Medline TA: Clin Pharm Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 152-61 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calorimetry Fat Emulsions, Intravenous / adverse effects, therapeutic use Humans Lung / physiopathology Muscles / physiopathology Nutrition Disorders / etiology, physiopathology Nutritional Physiological Phenomena* Parenteral Nutrition, Total Respiratory Tract Diseases / complications, physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Fat Emulsions, Intravenous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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