Document Detail

Nutrition markers in patients after heart surgery.
MedLine Citation:
PMID:  20375421     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Nutrition support is an important aspect of multidisciplinary approaches in cardiology rehabilitation. However, little is known about the impact of a patient's nutrition status on recovery after elective heart surgery. The authors assessed changes in nutrition markers in patients undergoing postsurgical rehabilitation, and tested their correlation with systemic inflammatory responses and clinical outcomes to determine the adequacy of the prescribed dietary regimen. METHODS: Plasma concentrations of nutrition biomarkers were measured in 50 nondiabetic patients upon admission to a cardiology rehabilitation unit after coronary artery bypass grafting or mitral and/or aortic valve replacement (D0), and again 16 days later (D16). RESULTS: On D16, low plasma albumin increased, anemia improved, and high levels of inflammation markers declined. Vitamins remained stable within normal values, with the exception of vitamin B12, which decreased significantly from 516 +/- 341 to 445 +/- 212 ng/mL (P = .007). Blood glucose was >110 mg/dL in 51% of the patients at baseline; this proportion did not decline after rehabilitation. Overweight patients (body mass index >25 kg/m(2)) were prevalent (58%). They showed a slightly but not significantly greater inflammatory response and had a higher incidence of infective complications than the normal-weight group, but similar levels of nutrition markers. CONCLUSIONS: The standard dietary regimen followed during cardiological rehabilitation after major cardiovascular surgery aids recovery from surgical insult, but fails to normalize high glucose levels. Vitamin B12 supplementation should be encouraged because of its substantial reduction during the rehabilitation period.
Vittorio Racca; Paolo Castiglioni; Vittorino Ripamonti; Simona Bertoli; Maria Gaetana Calvo; Maurizio Ferratini
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  34     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-04-08     Completed Date:  2010-07-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  143-50     Citation Subset:  IM    
Unit? Operativa Cardiologia Riabilitativa, IRCCS "Santa Maria Nascente" Fondazione Don C. Gnocchi, Milan, Italy.
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MeSH Terms
Anemia / blood*,  etiology
Biological Markers / blood
Blood Glucose / metabolism
Coronary Artery Bypass
Diet / standards*
Heart Diseases / blood*,  complications,  surgery
Heart Valve Prosthesis Implantation
Hyperglycemia / blood,  etiology
Inflammation / blood*,  etiology
Middle Aged
Nutritional Status*
Nutritional Support
Overweight / blood,  complications
Postoperative Complications / blood*
Serum Albumin / metabolism*
Vitamin B 12 / blood,  therapeutic use
Vitamins / blood,  therapeutic use
Reg. No./Substance:
0/Biological Markers; 0/Blood Glucose; 0/Serum Albumin; 0/Vitamins; 68-19-9/Vitamin B 12
Comment In:
JPEN J Parenter Enteral Nutr. 2010 Mar-Apr;34(2):163-8   [PMID:  19910527 ]

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