Document Detail


Nutrition and kidney in preterm infant.
MedLine Citation:
PMID:  22394021     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In pre- and post-natal period nutrition can influence the function of many organs, including the kidneys. Intrauterine growth restriction and low weight at birth are associated with reduced nephron number, a risk factor for later cardiovascular and renal diseases. The development of such adult diseases may be favored, in animals, by additional risk factors, including postnatal overnutrition and/or rapid postnatal growth. In preterm infants, during the first weeks of life, high values of serum urea are presents due to immaturity of the renal function. Thus the urea cannot be used in the first weeks of life as a parameter to evaluate the adequacy of protein intake. In comparison with older infants, healthy preterm infants, fed on human milk and adapted formulas, show a lower renal solute load because the higher growth rate associated with a raised nitrogen and mineral retention rate. Preterm infants are vulnerable to disturbances of acid-base metabolism, with a predisposition to metabolic acidosis due to a transient age-related low renal capacity for net acid excretion.
Authors:
Mario De Curtis; Jacques Rigo
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-6
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Dipartimento di Pediatria e Neuropsichiatria Infantile, Sapienza-Università ; Di Roma.
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