Document Detail

Nutrition in Inflammatory Bowel Disease.
MedLine Citation:
PMID:  21825089     Owner:  NLM     Status:  Publisher    
The diet of industrialized nations may contribute to the pathogenesis of both ulcerative colitis (UC) and Crohn disease (CD). Malnutrition is relatively unusual in UC, but in CD, which often affects the small intestine, it is frequent and may be severe. Nutrition support is therefore frequently indicated. First principles of artificial nutrition can be applied effectively using the gut whenever possible. Parenteral nutrition is generally required only in those with short bowel syndrome. An increasing literature (especially in pediatrics) favors the use of defined exclusive enteral nutrition (EN) in the primary treatment of active CD. Controlled trials are, however, lacking, and recommendations are accordingly not of the highest rank. It appears that in this context, simple polymeric regimens are usually sufficient, and there is currently insufficient evidence to make a strong recommendation for disease-specific feeds. In the maintenance of remission in CD, controlled data demonstrate that defined EN reduces the risk of relapse requiring steroid treatment. There are no data in support of primary nutrition therapy in UC either in management of the acute flare or in maintenance. In conclusion, nutrition therapy in adults with inflammatory bowel disease is probably both undervalued and underused, but the evidence base needs to be strengthened to confirm its efficacy, determine better those patients most likely to benefit, and optimize the regimens to be employed. (JPEN J Parenter Enteral Nutr. XXXX;XX:xxx-xxx).
Alastair Forbes; Emma Goldesgeyme; Emma Paulon
Related Documents :
23102569 - Serological markers of erosive hand osteoarthritis.
21825089 - Nutrition in inflammatory bowel disease.
17291769 - Clubbed thiazoles by maos: a novel approach to cyclin-dependent kinase 5/p25 inhibitors...
3780919 - Senile plaques as aberrant sprout-stimulating structures.
10459279 - Mortality from alzheimer's disease: an update.
12154149 - Subcortical hyperintensities in alzheimer's disease: associated clinical and metabolic ...
19527079 - Chronic intestinal pseudo-obstruction: a diagnosis to be considered.
6673269 - Cryogel studies for the optimization of cryofiltration (cf) therapy.
22922229 - Seven newly identified loci for autoimmune thyroid disease.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-8
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  -     ISSN:  0148-6071     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
University College Hospital.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The Role of Parenteral Lipids in the Development of Advanced Intestinal Failure-Associated Liver Dis...
Next Document:  Maintenance of Parenteral Nutrition Volume Reduction, Without Weight Loss, After Stopping Teduglutid...