Document Detail


[Nutrition and Phosphorus - New progress and problem - . The roles of intestinal and renal sodium dependent phosphate transporters in phosphate homeostasis].
MedLine Citation:
PMID:  23023625     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Inorganic phosphate (Pi) is an essential nutrient for several biological functions, including intracellular signal transduction, the production and function of cell membranes, and energy exchange. To achieve these functions, a transport system is required to transfer Pi across hydrophobic cell membranes. Pi (re) absorption in the small intestine and renal proximal tubules is important for Pi homeostasis. Three types of NaPi transporters (types I - III ) have been identified : solute carrier series SLC17A1 (NPT1/NaPi- I /OATv1) , SLC34 (NaPi- II a, NaPi- II b, NaPi- II c) , and SLC20 (PiT1, PiT2) , respectively. In this review, we discuss the role of NaPi transporters in Pi homeostasis.
Authors:
Hiroko Segawa; Shohei Sasaki; Tomo Mukai; Mai Manabe; Shinsuke Kido; Sawako Tatsumi; Kenichi Miyamoto
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Clinical calcium     Volume:  22     ISSN:  0917-5857     ISO Abbreviation:  Clin Calcium     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433326     Medline TA:  Clin Calcium     Country:  Japan    
Other Details:
Languages:  jpn     Pagination:  1469-76     Citation Subset:  IM    
Affiliation:
Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School, Japan.
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