Document Detail


Nutrigenomics: a case for the common soil between cardiovascular disease and cancer.
MedLine Citation:
PMID:  18850195     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The border between health and disease is often set by a complex equilibrium between two elements, genetics on one hand, lifestyle on the other, To know it better, means to give new weapons, often crucial, in the hands of the doctors and their patients. It also means to adjust therapies, to find out which drug is good for a patient and which prevention strategy will work better for him/her. Nutrigenomics is an approach to individualize or personalize food and nutrition, and ultimately health, by tailoring the food to the individual genotype. In this review, we present the interaction between certain genetic polymorphisms and diet and increased cardiovascular or cancer risk. It is, indeed, now clear that a large number of bioactive food components may provide risk or protection at several stages of both atherosclerosis and cancer formation processes. We are giving here few examples of gene-food interactions relevant for both the risk of cardiovascular disease and cancer, since a common soil could exist in the genesis of cardiovascular disease and of some types of cancer (mainly gastrointestinal tract and hormone-dependent).
Authors:
Licia Iacoviello; Iolanda Santimone; Maria Carmela Latella; Giovanni de Gaetano; Maria Benedetta Donati
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Genes & nutrition     Volume:  3     ISSN:  1555-8932     ISO Abbreviation:  Genes Nutr     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-10-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101280108     Medline TA:  Genes Nutr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  19-24     Citation Subset:  -    
Affiliation:
Laboratory of Genetic and Environmental Epidemiology, Research Laboratories, "John Paul II" Centre for High Technology Research and Education in Biomedical Sciences, Catholic University, Largo Gemelli, 1, 86100, Campobasso, Italy, licia.iacoviello@rm.unicatt.it.
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