Document Detail

Nutrient supplementation approaches in the treatment of ADHD.
MedLine Citation:
PMID:  19344299     Owner:  NLM     Status:  MEDLINE    
Attention-deficit/hyperactivity disorder (ADHD) is a chronic, debilitating psychiatric illness that often co-occurs with other common psychiatric problems. Although empirical evidence supports pharmacological and behavioral treatments, side effects, concerns regarding safety and fears about long-term use all contribute to families searching for alternative methods of treating the symptoms of ADHD. This review presents the published evidence on supplementation, including single ingredients (e.g., minerals, vitamins, amino acids and essential fatty acids), botanicals and multi-ingredient formulas in the treatment of ADHD symptoms. In most cases, evidence is sparse, mixed and lacking information. Of those supplements where we found published studies, the evidence is best for zinc (two positive randomized, controlled trials); there is mixed evidence for carnitine, pycnogenol and essential fatty acids, and more research is needed before drawing conclusions about vitamins, magnesium, iron, SAM-e, tryptophan and Ginkgo biloba with ginseng. To date, there is no evidence to support the use of St John's wort, tyrosine or phenylalanine in the treatment of ADHD symptoms. Multi-ingredient approaches are an intriguing yet under-researched area; we discuss the benefits of this approach considering the heterogeneous nature of ADHD.
Julia J Rucklidge; Jeanette Johnstone; Bonnie J Kaplan
Related Documents :
681979 - Essential fatty acid deficiency and cns myelin. biochemical and morphological observati...
824609 - Correction of essential fatty acid deficiency in newborn infants by cutaneous applicati...
12940929 - Essential fatty acid status in paediatric crohn's disease: relationship with disease ac...
6169979 - An expanded concept of "insurance" supplementation--broad-spectrum protection from card...
23399279 - Anti-ovarian cancer potential of two acidic polysaccharides from the rhizoma of menispe...
11026619 - Calcium deficiency modifies polyunsaturated fatty acid metabolism in growing rats.
11919549 - Conversion of 7 alpha-hydroxycholesterol to bile acid in human subjects: is there an al...
21696609 - Polyunsaturated fatty acids in various macroalgal species from north atlantic and tropi...
10557239 - The correlation of profiles of surface ph and elongation growth in maize roots.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert review of neurotherapeutics     Volume:  9     ISSN:  1744-8360     ISO Abbreviation:  Expert Rev Neurother     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-06     Completed Date:  2009-06-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101129944     Medline TA:  Expert Rev Neurother     Country:  England    
Other Details:
Languages:  eng     Pagination:  461-76     Citation Subset:  IM    
Department of Psychology, University of Canterbury, Private Bag 4800, Christchurch 8140, New Zealand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acids / therapeutic use
Attention Deficit Disorder with Hyperactivity / diet therapy*
Complementary Therapies / methods*
Dietary Supplements*
Fatty Acids, Essential / therapeutic use
Minerals / therapeutic use
Vitamins / therapeutic use
Reg. No./Substance:
0/Amino Acids; 0/Fatty Acids, Essential; 0/Minerals; 0/Vitamins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Happiness and neurological diseases.
Next Document:  Interventions to promote the evidence-based care of children with ADHD in primary-care settings.