Document Detail


Nutrient and environmental growth factors for nine oral small-sized spirochete strains containing one endoflagellum from each cell end.
MedLine Citation:
PMID:  2719849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present investigation was carried out in order to obtain better information about the growth requirements of small-sized spirochetes containing one endoflagellum from each cell end. Nine strains of such spirochetes were isolated from subgingival plaque in patients suffering from advanced marginal periodontitis. The strains were maintained in fluid NOS medium with 0.07% Noble Agar. The following environmental factors were studied: Oxygen in the incubation atmosphere and the pH value of the medium. The following nutrient factors were studied: Rabbit serum, heart infusion and trypticase, bovine albumin, human globulin, long-chain fatty acids, volatile fatty acids, steroids, amino acids, carbohydrates, and Na-bicarbonate. Growth was normally determined after 3 days' incubation at 35 degrees C by counting numbers of spirochete cells in a Petroff-Hausser counting chamber. All strains tolerated 3% oxygen in the atmosphere and the pH-optimum was 7.5. Rabbit serum was found not to be an essential nutrient factor. Human globulin stimulated growth, while bovine albumin inhibited growth. Heart infusion and trypticase influenced growth moderately. Of the remaining nutrient factors the long-chain fatty acids inhibited growth and the volatile fatty acids did not affect growth, while certain carbohydrates, especially glucose, stimulated growth. Na-bicarbonate in low concentrations stimulated growth, while higher concentrations inhibited growth.
Authors:
N E Fiehn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica     Volume:  97     ISSN:  0903-4641     ISO Abbreviation:  APMIS     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-06-28     Completed Date:  1989-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8803400     Medline TA:  APMIS     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  287-96     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Royal Dental College, Copenhagen, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood / metabolism
Carbohydrate Metabolism
Culture Media
Dental Plaque / microbiology
Flagella
Humans
Hydrogen-Ion Concentration
Oxygen Consumption
Periodontitis / microbiology
Proteins / metabolism
Rabbits
Spirochaetales / growth & development*,  metabolism
Chemical
Reg. No./Substance:
0/Culture Media; 0/Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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