Document Detail


Nutrient accretion in preterm infants fed formula with different protein:energy ratios.
MedLine Citation:
PMID:  9226525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although standard formulas for preterm infants promote intrauterine rates of weight gain, fat deposition in preterm infants fed these formulas has been reported to be considerably higher than that in the fetus. We hypothesized that a preterm infant formula with a higher protein:energy (P:E) ratio would promote accretion rates of fat, fat-free mass, and minerals closer to those of the fetus. METHODS: As part of a larger study to determine whether accretion rates of fat and fat-free mass closer to those of the fetus can be achieved with a higher P:E ratio, we present a descriptive analysis of 72-h nutrient balance studies performed on a subset (n = 15/30) of the infants randomly assigned to be fed formula with a P:E ratio of either 3.2 g/100 kcal or 2.6 g/100 kcal. RESULTS: Despite the higher intake and net absorption of nitrogen by infants fed the higher P:E formula, there was no statistically significant difference in net nitrogen retention between groups. There also were no statistically significant differences between groups in digestible energy, metabolizable energy, energy expenditure, or energy storage. Thus, partitioning of stored energy as protein and fat did not differ between groups. The retention of calcium, phosphorus, sodium, potassium, copper, and zinc also did not differ between groups, and nitrogen intake did not affect mineral retention. CONCLUSIONS: In this study, formula for preterm infants with a P:E ratio of 3.2 g/100 kcal vs. 2.6 g/100 kcal provided no apparent benefit in terms of the proportion of fat to lean tissue accretion as determined from nutrient balance data.
Authors:
A K Fairey; N F Butte; N Mehta; M Thotathuchery; R J Schanler; W C Heird
Related Documents :
8126625 - Effects of different formula feeds on the developmental pattern of urinary bile acid ex...
20216095 - Partially hydrolyzed 100% whey protein infant formula and reduced risk of atopic dermat...
3397845 - Intestinal milk-bolus obstruction in formula-fed premature infants given high doses of ...
11045835 - Cutaneous application of vegetable oil as a coadjutant in the nutritional management of...
3982875 - Vitamin a status of neonates with bronchopulmonary dysplasia.
15644825 - The parkland memorial hospital experience in ensuring compliance with universal newborn...
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  25     ISSN:  0277-2116     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-11-18     Completed Date:  1997-11-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-45     Citation Subset:  IM    
Affiliation:
Southern Mississippi Neonatology, Hattiesburg, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Calcium / blood,  metabolism
Cohort Studies
Copper / metabolism
Dietary Fats / metabolism
Dietary Proteins / administration & dosage*
Energy Intake / physiology*
Energy Metabolism / physiology
Female
Humans
Infant
Infant Food* / analysis,  standards
Infant Nutritional Physiological Phenomena*
Infant, Low Birth Weight / blood,  physiology*
Infant, Newborn
Infant, Premature / blood,  physiology*
Magnesium / blood,  metabolism
Male
Minerals / metabolism
Nitrogen / metabolism
Phosphorus / blood,  metabolism
Potassium / metabolism
Sodium / metabolism
Zinc / metabolism
Grant Support
ID/Acronym/Agency:
M01 RR-00188-30/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Dietary Fats; 0/Dietary Proteins; 0/Minerals; 7439-95-4/Magnesium; 7440-09-7/Potassium; 7440-23-5/Sodium; 7440-50-8/Copper; 7440-66-6/Zinc; 7440-70-2/Calcium; 7723-14-0/Phosphorus; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Can the histologic changes of cystic fibrosis-associated hepatobiliary disease be predicted by clini...
Next Document:  Modified cow's milk formula with reduced renal acid load preventing incipient late metabolic acidosi...