Document Detail

Numerical simulations of unsteady flows in a stenosed coronary bypass graft.
MedLine Citation:
PMID:  11523739     Owner:  NLM     Status:  MEDLINE    
Using the finite element method, physiological blood flows through a three-dimensional model of a coronary graft are numerically analysed. The model includes a stenosis shape in the host artery upstream from the anastomosis. Recirculating areas, secondary flows, wall shear stress (WSS) and spatial wall shear stress gradients (WSSGs) are studied for different flow repartitions and at different times in the cycle. The temporal and spatial evolutions of the recirculating areas downstream from the stenosis, their interactions with the flow issued from the graft and their associated WSSs highlight that the presence of the stenosis in the recipient artery is essential for prediction of the evolution of a grafting at the beginning of its implantation. The areas downstream from the stenosis expansion, non-existent for a host artery without stenosis, are submitted to low and oscillating WSS between -0.5 and 0 Nm(-2). The stagnation point on the recipient artery floor is subjected to high positive and negative WSSGnd values, and its location is dependent on the residual flow through the stenosis.
V Deplano; C Bertolotti; O Boiron
Related Documents :
12202169 - Evaluation of the haemocompatibility of titanium based biomaterials.
1521699 - Casting system effectiveness--measurement and theory.
12483479 - Biofilm material properties as related to shear-induced deformation and detachment phen...
19792319 - Flow conductance of a single nanohole.
20975199 - Interactive separating streak surfaces.
3599939 - An experimental study of newtonian and non-newtonian flow dynamics in a ventricular ass...
3584499 - Painful sickle cell crises precipitated by stopping prophylactic exchange transfusions.
9274469 - Blood groups lewis(b) and abh expression in gastric mucosa: lack of inter-relation with...
16387169 - Protective effect of diltiazem on hepatic ischemia-reperfusion injury in rats by improv...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical & biological engineering & computing     Volume:  39     ISSN:  0140-0118     ISO Abbreviation:  Med Biol Eng Comput     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-08-28     Completed Date:  2001-09-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704869     Medline TA:  Med Biol Eng Comput     Country:  England    
Other Details:
Languages:  eng     Pagination:  488-99     Citation Subset:  IM    
Laboratoire de Biomécanique Cardiovasculaire, Technopĵle de Château Gombert, Marseille, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Coronary Artery Bypass*
Graft Occlusion, Vascular / physiopathology*
Models, Cardiovascular*
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Computer simulation of the baroregulation in response to moderate dynamic exercise.
Next Document:  Myo-electric signals to augment speech recognition.