Document Detail


Numerical simulations of unsteady flows in a stenosed coronary bypass graft.
MedLine Citation:
PMID:  11523739     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using the finite element method, physiological blood flows through a three-dimensional model of a coronary graft are numerically analysed. The model includes a stenosis shape in the host artery upstream from the anastomosis. Recirculating areas, secondary flows, wall shear stress (WSS) and spatial wall shear stress gradients (WSSGs) are studied for different flow repartitions and at different times in the cycle. The temporal and spatial evolutions of the recirculating areas downstream from the stenosis, their interactions with the flow issued from the graft and their associated WSSs highlight that the presence of the stenosis in the recipient artery is essential for prediction of the evolution of a grafting at the beginning of its implantation. The areas downstream from the stenosis expansion, non-existent for a host artery without stenosis, are submitted to low and oscillating WSS between -0.5 and 0 Nm(-2). The stagnation point on the recipient artery floor is subjected to high positive and negative WSSGnd values, and its location is dependent on the residual flow through the stenosis.
Authors:
V Deplano; C Bertolotti; O Boiron
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical & biological engineering & computing     Volume:  39     ISSN:  0140-0118     ISO Abbreviation:  Med Biol Eng Comput     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-08-28     Completed Date:  2001-09-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704869     Medline TA:  Med Biol Eng Comput     Country:  England    
Other Details:
Languages:  eng     Pagination:  488-99     Citation Subset:  IM    
Affiliation:
Laboratoire de Biomécanique Cardiovasculaire, Technopĵle de Château Gombert, Marseille, France. deplano.valerie@esm2.imt-mrs.fr
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MeSH Terms
Descriptor/Qualifier:
Coronary Artery Bypass*
Graft Occlusion, Vascular / physiopathology*
Hemorheology*
Humans
Models, Cardiovascular*
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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