Document Detail


Numerical magnitude in the human parietal lobe; tests of representational generality and domain specificity.
MedLine Citation:
PMID:  15504334     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Behavioral evidence suggests that human adults have a single system for representing the numerical magnitude of both symbolic numbers (e.g., Arabic digits) and nonsymbolic number stimuli (e.g., dot arrays). Brain imaging studies have implicated a specific parietal region in symbolic number processing, leading to the influential hypothesis that this region is the locus of a dedicated, domain-specific number system. Here we evaluated a prediction of this hypothesis, that this region should be activated not only by symbolic but also nonsymbolic number processing. Using nonsymbolic stimuli, we tested for higher parietal activations for number than for nonnumber comparison tasks (experiment 1), fMRI adaptation for numerosity repetition (experiment 2), and greater fMRI increases with increasing task difficulty for number than nonnumber tasks (experiment 3). None of these predictions were supported by the data, posing a serious challenge to the hypothesis that a single, domain-specific parietal region underlies both symbolic and nonsymbolic number representation.
Authors:
Miles Shuman; Nancy Kanwisher
Related Documents :
19843664 - Regional brain activation during verbal declarative memory in metastatic breast cancer.
14659494 - Dissociable brain mechanisms for inhibitory control: effects of interference content an...
19861234 - Language network dysfunction as a predictor of outcome in youth at clinical high risk f...
22573224 - For a new look at 'lexical errors': evidence from semantic approximations with verbs in...
16568354 - Goal-directed action representation in autism.
19653784 - Fanning the flames of prejudice: the influence of specific incidental emotions on impli...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Neuron     Volume:  44     ISSN:  0896-6273     ISO Abbreviation:  Neuron     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-26     Completed Date:  2005-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8809320     Medline TA:  Neuron     Country:  United States    
Other Details:
Languages:  eng     Pagination:  557-69     Citation Subset:  IM    
Affiliation:
Department of Psychology, Harvard University, Cambridge, MA 02138 USA. mshuman@fas.harvard.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Brain Mapping
Dominance, Cerebral / physiology*
Female
Humans
Image Processing, Computer-Assisted / methods
Magnetic Resonance Imaging / methods
Male
Mental Processes / physiology*
Oxygen / blood
Parietal Lobe / blood supply,  physiology*
Photic Stimulation / methods
Reaction Time / physiology
Semantics*
Time Factors
Visual Perception / physiology*
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Tuning curves for approximate numerosity in the human intraparietal sulcus.
Next Document:  Src protein-tyrosine kinase structure and regulation.