Document Detail

Numerical magnitude in the human parietal lobe; tests of representational generality and domain specificity.
MedLine Citation:
PMID:  15504334     Owner:  NLM     Status:  MEDLINE    
Behavioral evidence suggests that human adults have a single system for representing the numerical magnitude of both symbolic numbers (e.g., Arabic digits) and nonsymbolic number stimuli (e.g., dot arrays). Brain imaging studies have implicated a specific parietal region in symbolic number processing, leading to the influential hypothesis that this region is the locus of a dedicated, domain-specific number system. Here we evaluated a prediction of this hypothesis, that this region should be activated not only by symbolic but also nonsymbolic number processing. Using nonsymbolic stimuli, we tested for higher parietal activations for number than for nonnumber comparison tasks (experiment 1), fMRI adaptation for numerosity repetition (experiment 2), and greater fMRI increases with increasing task difficulty for number than nonnumber tasks (experiment 3). None of these predictions were supported by the data, posing a serious challenge to the hypothesis that a single, domain-specific parietal region underlies both symbolic and nonsymbolic number representation.
Miles Shuman; Nancy Kanwisher
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Neuron     Volume:  44     ISSN:  0896-6273     ISO Abbreviation:  Neuron     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-26     Completed Date:  2005-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8809320     Medline TA:  Neuron     Country:  United States    
Other Details:
Languages:  eng     Pagination:  557-69     Citation Subset:  IM    
Department of Psychology, Harvard University, Cambridge, MA 02138 USA.
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MeSH Terms
Brain Mapping
Dominance, Cerebral / physiology*
Image Processing, Computer-Assisted / methods
Magnetic Resonance Imaging / methods
Mental Processes / physiology*
Oxygen / blood
Parietal Lobe / blood supply,  physiology*
Photic Stimulation / methods
Reaction Time / physiology
Time Factors
Visual Perception / physiology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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