Document Detail


Numerical investigation of the hemodynamics in anatomically realistic lateral cerebral aneurysms.
MedLine Citation:
PMID:  21096182     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemodynamically induced stress plays an important role in the progression and rupture of cerebral aneurysms. The current work describes computational fluid dynamics (CFD) simulations in anatomically realistic models of cerebral aneurysms. Twenty lateral aneurysms models were investigated. The models were obtained from three-dimensional rotational angiographic imaging data and CFD were studied under the same physiologically representative waveform of inflow. The flow was assumed to be laminar, non-Newtonian, and incompressible. The CFD models were solved with the finite elements package ADINA. Predictions of velocity field and wall shear stress (WSS) on the aneurysms were compared for the different cases. Linear correlations between the WSS on the aneurysm fundus at peak systole for lateral aneurysms with an area index were found.
Authors:
Alvaro Valencia; Julio Munizaga; Rodrigo Rivera; Eduardo Bravo
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2010     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-24     Completed Date:  2011-03-30     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2616-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aneurysm / pathology
Angiography / methods
Cerebral Angiography
Computer Simulation
Disease Progression
Fourier Analysis
Hemodynamics
Humans
Hydrodynamics
Imaging, Three-Dimensional
Intracranial Aneurysm / diagnosis*,  physiopathology*
Linear Models
Models, Cardiovascular
Models, Theoretical
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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