Document Detail

Numerical methods and workstation for the quantitative analysis of real-time myocardial contrast echocardiography.
MedLine Citation:
PMID:  20129869     Owner:  NLM     Status:  MEDLINE    
Using the quantitative analysis of real-time myocardial contrast echocardiography (RT MCE), clinicians can assess the myocardial perfusion of patients, noninvasively and accurately. We designed a workstation to assist clinicians to automatically implement the accurate analysis of RT MCE. The workstation can compute some hemodynamic parameters of myocardial microcirculation, e.g., myocardial blood flow, myocardial blood flow mean velocity, and myocardial blood volume. Our new methods involved in the quantitative analysis of RT MCE are summarized as follows. 1) A novel orthogonal array optimization (OAO) technique was proposed and used to estimate the unknown parameters of the nonlinear model to guarantee numerical stability. 2) Brox's coarse-to-fine warping optical flow technique was employed to automatically track the region of interest located inside the myocardial area to ensure the accuracy of the quantitative analysis. Finally, we illustrate some examples of clinical studies to indicate the effectiveness of the system and the reliability of the methods.
Feng-rong Sun; Ming-qiang Zhang; Xiao-bo Jia; Xiao-jing Wang; Gui-hua Yao; Yun Zhang
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Publication Detail:
Type:  Journal Article     Date:  2010-02-02
Journal Detail:
Title:  IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society     Volume:  14     ISSN:  1558-0032     ISO Abbreviation:  IEEE Trans Inf Technol Biomed     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-12-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9712259     Medline TA:  IEEE Trans Inf Technol Biomed     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1204-10     Citation Subset:  IM    
School of Information Science and Engineering, Shandong University, Jinan 250100, China.
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MeSH Terms
Contrast Media
Echocardiography / methods*
Heart / anatomy & histology,  physiology*
Image Processing, Computer-Assisted / methods*
Nonlinear Dynamics
Regression Analysis
Reg. No./Substance:
0/Contrast Media

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