Document Detail

Nucleotide sequence of the thymidylate synthetase gene (thyP3) from the Bacillus subtilis phage phi 3T.
MedLine Citation:
PMID:  3924741     Owner:  NLM     Status:  MEDLINE    
The thyP3 gene, encoding thymidylate synthetase, from the Bacillus subtilis phage phi 3T has been cloned and the nucleotide sequence determined. The derived amino acid sequence indicates a subunit Mr of 32 748. The primary amino acid sequence is compared with the sequences of the analogous proteins specified by Escherichia coli (thyA), Lactobacillus casei, (thyA) and phage T4 (td). Extensive conservation exists in all four sequences implying a shared tertiary structure.
E Kenny; T Atkinson; B S Hartley
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gene     Volume:  34     ISSN:  0378-1119     ISO Abbreviation:  Gene     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-21     Completed Date:  1985-08-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7706761     Medline TA:  Gene     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  335-42     Citation Subset:  IM    
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MeSH Terms
Amino Acid Sequence
Bacillus subtilis / genetics*
Bacteriophages / enzymology,  genetics*
Base Sequence
Cloning, Molecular
Escherichia coli / genetics
Genes, Bacterial
Genes, Viral
Lactobacillus casei / genetics
Methyltransferases / genetics*
T-Phages / genetics
Thymidylate Synthase / genetics*
Reg. No./Substance:
EC 2.1.1.-/Methyltransferases; EC Synthase

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