Document Detail

Nucleomorphometric analysis of canine cutaneous mast cell tumours.
MedLine Citation:
PMID:  16045919     Owner:  NLM     Status:  MEDLINE    
Thirty-five canine cutaneous mast cell tumours (CCMCTs) were analysed by computerized nuclear morphometry. In each case, the nuclei of at least 100 neoplastic cells were measured, and the mean nuclear area (MNA), mean nuclear perimeter (MNP) and mean nuclear form factor (FF) were calculated. Significant differences in respect of MNA and MNP occurred between tumours of grades I and III and between those of grades II and III (P<0.01) but not between tumours of grades I and II (P>0.01). No significant differences in respect of FF were observed between tumours of different grades. The results obtained indicate that nuclear morphometric analysis may assist in the grading of CMCTs.
P Maiolino; M Cataldi; O Paciello; B Restucci; G De Vico
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of comparative pathology     Volume:  133     ISSN:  0021-9975     ISO Abbreviation:  J. Comp. Pathol.     Publication Date:    2005 Aug-Oct
Date Detail:
Created Date:  2005-08-15     Completed Date:  2005-10-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0102444     Medline TA:  J Comp Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  209-11     Citation Subset:  IM    
Dipartimento di Patologia e Sanità Animale, Settore di Anatomia Patologica, Facoltà di Medicina Veterinaria, Università degli Studi di Napoli Federico II, Via Delpino 1, 80137 Napoli, Italy.
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MeSH Terms
Cell Nucleus / pathology*
Dog Diseases / pathology*,  surgery
Mast-Cell Sarcoma / classification,  secondary,  veterinary*
Neoplasm Recurrence, Local / veterinary
Neoplasm Staging / veterinary
Skin Neoplasms / classification,  pathology,  veterinary*

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