| Nucleolar organizer regions in small cell carcinoma of lung. | |
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MedLine Citation:
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PMID: 8007047 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Agyrophilic staining of nucleolar organizer regions (NOR) has been used to differentiate between cells of small cell carcinoma and lymphocytes in tissue specimens. We used cytologic smears which were previously Papanicolaou-destained to study the one-step agyrophilic staining technique for nucleolar organizer regions (AgNOR) in cell of small cell carcinoma and lymphocyte. The purposes of this study were to assess the feasibility and usefulness of AgNOR staining in diagnostic cytology and to try to set up a procedure that could be used on prestained smears for retrospective study. While the NOR of each lymphocyte appeared to be one round dot after AgNOR staining, the NOR of cell of small cell carcinoma showed dots, slightly variable in size and shape. The mean number of NOR was significantly higher (p < 0.01) in cells of small cell carcinoma (4.7 +/- 0.7) than in lymphocytes (1.4 +/- 0.4). In conclusion, AgNOR staining was demonstrated to be a useful method to differentiate between cells of small cell carcinoma and lymphocyte in Papanicolaou-destained smears. |
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Authors:
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M S Lin; J J Hwang; I W Chong; M S Tsai |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences Volume: 10 ISSN: 0257-5655 ISO Abbreviation: Gaoxiong Yi Xue Ke Xue Za Zhi Publication Date: 1994 Apr |
Date Detail:
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Created Date: 1994-07-20 Completed Date: 1994-07-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8603880 Medline TA: Gaoxiong Yi Xue Ke Xue Za Zhi Country: TAIWAN |
Other Details:
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Languages: eng Pagination: 182-5 Citation Subset: D; IM |
Affiliation:
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Department of Internal Medicine, Kaohsiung Medical College, Taiwan, Republic of China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Small Cell
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pathology* Humans Lung Neoplasms / pathology* Lymphocytes / pathology Nucleolus Organizer Region / pathology* Retrospective Studies |
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