| Nucleolar organizer regions in differentiated preneoplastic and neoplastic endometrial lesions. | |
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MedLine Citation:
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PMID: 10087419 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was the quantitative assessment of nucleolar organizer regions (NORs) in the cells of preneoplastic and neoplastic endometrial lesions. Retrospective analysis included tissue material obtained from 87 patients with simple and complex hyperplasia with or without atypia and well-differentiated stage-I endometrial adenocarcinoma. Sections were made from routine paraffin blocks and stained with AgNO3. The mean number of AgNORs per cell was determined. The results obtained indicate that the evaluation of proliferative activity of cells expressed by AgNOR count can help in the distinction between atypical hyperplasia and well-differentiated adenocarcinoma, and thus can serve as a useful pathological criterion. |
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Authors:
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S Terlikowski; A Lenczewski; S Sulkowski; M Kulikowski |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 47 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 1999 |
Date Detail:
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Created Date: 1999-05-06 Completed Date: 1999-05-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 205-9 Citation Subset: IM |
Affiliation:
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Department of Gynecology and Obstetrics, Medical University of Bialystok, Poland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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ultrastructure Cell Differentiation Endometrial Neoplasms / ultrastructure* Female Humans Hyperplasia Nucleolus Organizer Region / ultrastructure* Precancerous Conditions / ultrastructure* Retrospective Studies Silver Staining Tissue Embedding |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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