| Nucleic acids and protein content of some fetal and neonatal rat organs after insulin treatment. | |
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MedLine Citation:
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PMID: 6164549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 17 1/2--21 1/2 day-old fetuses and 1--4 day-old rats the DNA, RNA and protein content of the liver, heart and brain was daily investigated 6 hours after injecting approximately 40 mU . g-1 insulin. The DNA content in the mentioned organs was not affected by the insulin. The RNA content in the fetal and neonatal brain and neonatal heart was significantly elevated, while the liver RNA was not altered. Only in the 4 day-old brain did the protein content increase. The experimental dates indicate that the cell RNA content of some perinatal tissues can be elevated by insulin depending on the type of tissue and its developmental stage. |
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Authors:
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J Koppel; S Kuchár; S Mózes; K Bod'a |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Endokrinologie Volume: 77 ISSN: 0013-7251 ISO Abbreviation: Endokrinologie Publication Date: 1981 Mar |
Date Detail:
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Created Date: 1981-07-09 Completed Date: 1981-07-09 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370675 Medline TA: Endokrinologie Country: GERMANY, EAST |
Other Details:
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Languages: eng Pagination: 95-100 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Brain Chemistry / drug effects* DNA / analysis Fetus Heart / drug effects Insulin / pharmacology* Liver / analysis*, drug effects Myocardium / analysis* Proteins / analysis RNA / analysis Rats |
| Chemical | |
Reg. No./Substance:
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0/Proteins; 11061-68-0/Insulin; 63231-63-0/RNA; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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