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Nucleic acid sample preparation for in vitro molecular diagnosis: from conventional techniques to biotechnology.
MedLine Citation:
PMID:  22819926     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Nucleic acid (DNA and RNA)-based molecular diagnosis is a promising laboratory technique because of its ability to identify disease accurately. However, one of its disadvantages is the inevitable purification and detection of nucleic acids from other contaminated entities. Different nano- and microparticles have been developed for use in an advanced, efficient high-throughput autosystem for the purification and detection of nucleic acid samples for use in molecular diagnoses. In this review, we discuss recent advances in the development of particle-based nucleic acid purification and detection.
Authors:
Md Mahbubor Rahman; Abdelhamid Elaissari
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-19
Journal Detail:
Title:  Drug discovery today     Volume:  -     ISSN:  1878-5832     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9604391     Medline TA:  Drug Discov Today     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Université Lyon-1, Villeurbanne, CNRS, UMR 5007, LAGEP - CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France.
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