| Nucleic acid molecules: new microdiffusion technique for visualization. | |
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MedLine Citation:
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PMID: 4299805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A microdiffusion technique, developed for visualization of nucleic acid molecules in the electron microscope, requires less than 0.01 microgram of nucleic acid. Although originally developed for free nucleic acids, the method can be applied to virion suspensions for direct visualization of their genomes; less than 10(10) virions per milliliter are required. Results agree well with those yielded by the diffusion technique of Lang, Kleinschmidt, and Zahn. |
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Authors:
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H D Mayor; L E Jordan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 161 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1968 Sep |
Date Detail:
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Created Date: 1968-10-24 Completed Date: 1968-10-24 Revised Date: 2011-12-02 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1246-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adsorption Centrifugation, Density Gradient Cytochromes DNA, Viral* Diffusion Genetics, Microbial Methods Microscopy, Electron Molecular Biology Nucleic Acids* Papillomaviridae Polyomaviridae RNA, Viral* Simian virus 40 Virology* |
| Chemical | |
Reg. No./Substance:
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0/Cytochromes; 0/DNA, Viral; 0/Nucleic Acids; 0/RNA, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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